Smallpox

Subterranean Tremors deals X damage to each creature without flying. If X is 4 or more, destroy all artifacts. If X is 8 or more, create an 8/8 red Lizard creature token.

Target creature gets +2/+0 until end of turn. Create a Monster Role token attached to it. (If you control another Role on it, put that one into the graveyard. Enchanted creature gets +1/+1 and has trample.)

Put a +1/+1 counter on target creature you control, then it deals damage equal to its power to target creature an opponent controls.

Counter target spell with mana value 4 or greater.

Choose one — • Brotherhood's End deals 3 damage to each creature and each planeswalker. • Destroy all artifacts with mana value 3 or less.

Create three 1/1 white Rabbit creature tokens.

Cast this spell only before the combat damage step. Target creature gains trample and gets +X/+0 until end of turn, where X is its power. At the beginning of the next end step, destroy that creature if it attacked this turn.

Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.